SCHEMBL30006067

SCHEMBL30006067

CCCCC(Br)Cc1cccc(C)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.40
CCR1 P32246 1/20 0.34
CCR8 P51685 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
RAB9A P51151 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM1A O60341 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
PDE8B O95263 1/20 0.32
CXCR4 P61073 1/20 0.32
ALDH1A1 P00352 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30006319 0.94 KCNH2 (0.45) KCNH2CCR1CCR8SMN1; SMN2KMT2A
SCHEMBL30006203 0.84 ALDH1A1 (0.37) CCR1CCR8SMN1; SMN2NOS3NOS2
Hydrochloric Acid SCHEMBL4827329 0.79 BDKRB2 (0.46) KCNH2CCR1CCR8SMN1; SMN2NOS3
SCHEMBL23153062 0.75 CCR1 (0.38) KCNH2CCR1CCR8SMN1; SMN2NOS3
SCHEMBL681574 0.73 KCNH2 (0.64) KCNH2CCR1CCR8SMN1; SMN2NOS3
SCHEMBL10373980 0.72 KCNH2 (0.74) KCNH2CCR1CCR8SMN1; SMN2NOS3
SCHEMBL2614966 0.71 KDM4E (0.46) CCR1CCR8SMN1; SMN2NOS3NOS2
SCHEMBL16227752 0.70 KCNH2 (0.78) KCNH2CCR1CCR8SMN1; SMN2
SCHEMBL22299298 0.70 KCNH2 (0.78) KCNH2CCR1CCR8SMN1; SMN2
SCHEMBL16228298 0.70 KCNH2 (0.78) KCNH2CCR1CCR8SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907257-B Method for catalyzing non-activated olefin halogenated pyridine through visible light induction 中国科学院大连化学物理研究所 2023-11-24 CN disclosed
CN-114907257-A Method for catalyzing non-activated olefin halopyridination through visible light induction 中国科学院大连化学物理研究所 2022-08-16 CN disclosed