Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236376 | 0.87 | S1PR4 (0.50) | S1PR4PTGDR2RXRARXRBRXRG | |
| SCHEMBL17847407 | 0.86 | PTGDR2 (0.57) | S1PR4PTGDR2ALDH1A1HPGDTSHR | |
| SCHEMBL1632128 | 0.84 | S1PR4 (0.46) | S1PR4PTGDR2HPGDSLC6A4KDM1A | |
| SCHEMBL23907133 | 0.81 | HTR2A (0.41) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL18704596 | 0.81 | S1PR4 (0.54) | S1PR4PTGDR2RXRARXRBRXRG | |
| SCHEMBL16585038 | 0.78 | S1PR4 (0.44) | S1PR4PTGDR2RXRARXRBRXRG | |
| SCHEMBL3587016 | 0.78 | S1PR4 (0.48) | S1PR4PTGDR2SLC6A4KDM1ANPY1R | |
| SCHEMBL2950931 | 0.77 | S1PR1 (0.55) | S1PR4PTGDR2HPGDNPSR1LMNA | |
| SCHEMBL5568957 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRALOX15NPSR1 | |
| SCHEMBL22289887 | 0.76 | PTGDR2 (0.53) | S1PR4PTGDR2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |