SCHEMBL30006571

SCHEMBL30006571

[Ru+2].c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.52
CHUK O15111 1/20 0.52
DAPK3 O43293 1/20 0.52
JAK2 O60674 1/20 0.52
PRKD3 O94806 1/20 0.52
MAP4K4 O95819 1/20 0.52
PAK4 O96013 1/20 0.52
CSF1R P07333 1/20 0.52
RET P07949 1/20 0.52
IGF1R P08069 1/20 0.52
FGFR1 P11362 1/20 0.52
PRKACA P17612 1/20 0.52
FLT1 P17948 1/20 0.52
LTK P29376 1/20 0.52
GRK5 P34947 1/20 0.52
KDR P35968 1/20 0.52
MAP2K2 P36507 1/20 0.52
MAPK8 P45983 1/20 0.52
CSNK1A1 P48729 1/20 0.52
CDK8 P49336 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29461575 1.00 IKBKB (0.52) IKBKBCHUKDAPK3JAK2PRKD3
Hydrochloric Acid SCHEMBL8685286 1.00 IKBKB (0.52) IKBKBCHUKDAPK3JAK2PRKD3
Hydrochloric Acid SCHEMBL5322441 1.00 IKBKB (0.52) IKBKBCHUKDAPK3JAK2PRKD3
Hydrochloric Acid SCHEMBL3651629 1.00 IKBKB (0.52) IKBKBCHUKDAPK3JAK2PRKD3
Hydrochloric Acid SCHEMBL345453 1.00 IKBKB (0.52) IKBKBCHUKDAPK3JAK2PRKD3
Water SCHEMBL3153510 0.98 LRRK2 (0.50) IKBKBCHUKDAPK3JAK2PRKD3
SCHEMBL28859500 0.98 IKBKB (0.53) IKBKBCHUKDAPK3JAK2PRKD3
Benzene SCHEMBL28095234 0.98 IKBKB (0.53) IKBKBCHUKDAPK3JAK2PRKD3
SCHEMBL28868 0.98 IKBKB (0.53) IKBKBCHUKDAPK3JAK2PRKD3
Water SCHEMBL6948377 0.96 LRRK2 (0.49) IKBKBCHUKDAPK3JAK2PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384259-A Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2024-01-12 CN claimed
CN-112912386-B Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2023-10-20 CN claimed
CN-116855536-A Construct for real-time tracing of genomic spatial conformation and transcription products in living cells and uses thereof 生物岛实验室 2023-10-10 CN claimed
CN-113861268-B Cell penetrating peptides and methods of making and using the same 恩特拉达治疗学股份有限公司 2025-04-01 CN disclosed
CN-119136833-A Membrane translocation domain and uses thereof 俄亥俄州创新基金会 2024-12-13 CN disclosed
CN-113039191-B Nucleotide analogues 奇异基因组学系统公司 2024-07-16 CN disclosed
CN-117957022-A Antisense compounds and methods for targeting CUG repeats 安卓达治疗股份有限公司 2024-04-30 CN disclosed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN disclosed
CN-117897176-A Compositions and methods for modulating tissue distribution of intracellular therapeutic agents 恩特拉达治疗学股份有限公司 2024-04-16 CN disclosed
CN-117866042-A Disulfide-containing cell penetrating peptides and methods of making and using the same 俄亥俄州国家创新基金会 2024-04-12 CN disclosed
EP-4314016-A1 CYCLIC CELL PENETRATING PEPTIDES Entrada Therapeutics, Inc. (US) 2024-02-07 EP disclosed
CN-117384259-A Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2024-01-12 CN disclosed
CN-110114075-B Disulfide-containing cell penetrating peptides and methods of making and using the same 俄亥俄州国家创新基金会 2024-01-12 CN disclosed
CN-112912386-B Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2023-10-20 CN disclosed
CN-116855536-A Construct for real-time tracing of genomic spatial conformation and transcription products in living cells and uses thereof 生物岛实验室 2023-10-10 CN disclosed
EP-4117682-A1 MODIFIED NUCLEOTIDES AND USES THEREOF Singular Genomics Systems, Inc. (US) 2023-01-18 EP disclosed
EP-4110952-A2 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF Singular Genomics Systems, Inc. (US) 2023-01-04 EP disclosed
WO-2022251242-A1 COMPOSITIONS AND METHODS FOR MODIFYING DNA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-01 WO disclosed
WO-2022240758-A1 COMPOSITIONS AND METHODS FOR MODULATING GENE EXPRESSION ENTRADA THERAPEUTICS, INC. (US) 2022-11-17 WO disclosed
WO-2022213118-A1 CYCLIC CELL PENETRATING PEPTIDES ENTRADA THERAPEUTICS, INC. (US) 2022-10-06 WO disclosed