Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461575 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL8685286 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL30006571 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL5322441 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL3651629 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Water SCHEMBL3153510 | 0.98 | LRRK2 (0.50) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL28859500 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Benzene SCHEMBL28095234 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL28868 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Water SCHEMBL6948377 | 0.96 | LRRK2 (0.49) | IKBKBCHUKDAPK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250067712-A1 | Oxygen Sensing Composition and Method of Use | MAGDY IBRAHIM MOHAMED (US) | 2025-02-27 | — | — | US | claimed |
| CN-118931524-A | Fluorescent material and preparation and application thereof | 中国农业大学 | 2024-11-12 | — | — | CN | claimed |
| EP-4291090-A1 | OPTICAL BASED GLUCOSE SENSOR | Medtronic, Inc. (US) | 2023-12-20 | — | — | EP | claimed |
| US-20220169680-A1 | CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN | INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2022-06-02 | — | — | US | claimed |
| EP-3912989-A1 | CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN | Institute of Basic Medical Sciences Chinese Academy of Medical Sciences (CN) | 2021-11-24 | — | — | EP | claimed |
| US-10247712-B2 | Printable oxygen sensing composition | SUN CHEMICAL B.V. (NL) | 2019-04-02 | — | — | US | claimed |
| US-9518928-B2 | Optode for determining chemical parameters | UNIVERSITAET POTSDAM (DE) | 2016-12-13 | — | — | US | claimed |
| US-9459241-B2 | Printable oxygen sensing composition | SUN CHEMICAL B.V. (NL) | 2016-10-04 | — | — | US | claimed |
| EP-2805151-B1 | OPTODE FOR DETERMINING CHEMICAL PARAMETERS | UNIVERSITÄT POTSDAM (DE) | 2016-04-06 | — | — | EP | claimed |
| US-20160041135-A1 | CORE-SHELL NANOFIBER-BASED SENSORS | NATIONAL SCIENCE FOUNDATION | 2016-02-11 | — | — | US | claimed |
| EP-1121567-B1 | LUMINESCENT BRITTLE COATING IN STRAIN ANALYSIS | UNIV FLORIDA (US) | 2004-09-15 | — | — | EP | claimed |
| US-6327030-B1 | System, method, and coating for strain analysis | UNIVERSITY OF FLORIDA | 2001-12-04 | — | — | US | claimed |
| US-20010008445-A1 | System, method, and coating for strain analysis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2001-07-19 | — | — | US | claimed |
| EP-0745220-B1 | OPTICAL SENSORS | DIAMETRICS MEDICAL LTD (GB) | 2000-04-12 | — | — | EP | claimed |
| EP-0746757-A4 | A RATIOMETRIC FLUORESCENCE METHOD TO MEASURE OXYGEN | OPTICAL SENSORS INC (US) | 1999-10-20 | — | — | EP | claimed |
| US-5681532-A | OXYGEN PERMEABLE MEMBRANE OF A CURED PERFLUORINATED URETHANE POLYMER AND INCORPORATED THEREIN AN OXYGEN INDICTOR AND A REFERENCE DYE | OPTICAL SENSORS, INCORPORATED (US) | 1997-10-28 | — | — | US | claimed |
| US-5632958-A | Indicator containing perfluorinated polyurethane membranes for use in optical oxygen sensors | OPTICAL SENSORS INCORPORATED (US) | 1997-05-27 | — | — | US | claimed |
| EP-0746757-A1 | A RATIOMETRIC FLUORESCENCE METHOD TO MEASURE OXYGEN | OPTICAL SENSORS INCORPORATED (US) | 1996-12-11 | — | — | EP | claimed |
| US-5462880-A | Fluorinated polyurethane as permeable membrane | OPTICAL SENSORS INCORPORATED (US) | 1995-10-31 | — | — | US | claimed |
| WO-1995008107-A1 | A RATIOMETRIC FLUORESCENCE METHOD TO MEASURE OXYGEN | OPTICAL SENSORS INCORPORATED (US) | 1995-03-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10247712-B2 | Printable oxygen sensing composition | COXFA4L2, PPOX, PDE6B | IKBKB 4597/4885CHUK 4628/4885DAPK3 3722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.