Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8685286 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL30006571 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL5322441 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL3651629 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL345453 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Water SCHEMBL3153510 | 0.98 | LRRK2 (0.50) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL28859500 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Benzene SCHEMBL28095234 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL28868 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Water SCHEMBL6948377 | 0.96 | LRRK2 (0.49) | IKBKBCHUKDAPK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114414536-A | Preparation method of dissolved oxygen sensitive film based on fluorescence | 上海蓝长自动化科技有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-109187453-B | Preparation method of fluorescence method dissolved oxygen sensor diaphragm | 合肥莱瑞科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| US-12637489-B2 | Silicon containing modified nucleotide analogs | Singular Genomics Systems, Inc. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12630808-B2 | Modified archaeal family b polymerases | Singular Genomics Systems, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-04-07 | — | — | US | disclosed |
| US-12577271-B2 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-03-17 | — | — | US | disclosed |
| US-12503730-B2 | Detectable nucleotide analogues | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-12-23 | — | — | US | disclosed |
| US-20250361260-A1 | NUCLEOTIDE ANALOGUES | SINGULAR GENOMICS SYSTEMS INC (US) | 2025-11-27 | — | — | US | disclosed |
| US-12454683-B2 | Modified archaeal family B polymerases | Singular Genomics Systems, Inc. (US) | 2025-10-28 | — | — | US | disclosed |
| CN-108779138-B | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2022-06-17 | — | — | CN | disclosed |
| US-20220170092-A1 | METHODS FOR LONG READ SEQUENCING | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-06-02 | — | — | US | disclosed |
| CN-114414536-A | Preparation method of dissolved oxygen sensitive film based on fluorescence | 上海蓝长自动化科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | LG ELECTRONICS INC. (KR) | 2022-04-28 | — | — | US | disclosed |
| US-20220119780-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| US-20220119779-A1 | MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| WO-2022072374-A1 | LIGHT-CONTROLLED BIOORTHOGONAL TETRAZINE LIGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-07 | — | — | WO | disclosed |
| CN-109187453-B | Preparation method of fluorescence method dissolved oxygen sensor diaphragm | 合肥莱瑞科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630808-B2 | Modified archaeal family b polymerases | SSU72, POLB, POLQ | IKBKB 3157/4885CHUK 4019/4885DAPK3 3967/4885 |
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | NSUN2, CCRL2, NOP2 | IKBKB 2155/4885CHUK 1842/4885DAPK3 4007/4885 |
| US-12577271-B2 | Modified nucleotides and uses thereof | NUDT1, NSUN2, CCRL2 | IKBKB 2781/4885CHUK 2662/4885DAPK3 4017/4885 |
| US-12637489-B2 | Silicon containing modified nucleotide analogs | NSUN2, POLR2H, POLH | IKBKB 1906/4885CHUK 1758/4885DAPK3 4642/4885 |
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | POLL, POLB, POLN | IKBKB 3719/4885CHUK 3519/4885DAPK3 4365/4885 |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | NUDT21, CPSF7, DCLRE1A | IKBKB 3196/4885CHUK 3897/4885DAPK3 2386/4885 |
| US-20250361260-A1 | NUCLEOTIDE ANALOGUES | ADAR, NUDT1, NSUN2 | IKBKB 1525/4885CHUK 1659/4885DAPK3 3051/4885 |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | DNMT3A, POLB, POLM | IKBKB 3005/4885CHUK 3723/4885DAPK3 4554/4885 |
| US-12503730-B2 | Detectable nucleotide analogues | NT5C3B, NUDT1, RNGTT | IKBKB 3843/4885CHUK 4036/4885DAPK3 3542/4885 |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | POLRMT, NSUN2, NUDT1 | IKBKB 3162/4885CHUK 4057/4885DAPK3 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.