Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111049 | 1.00 | GPR3 (0.48) | GPR3KMT2ACA9CA12CA2 | |
| 1,6-Hexanediol SCHEMBL10762750 | 0.85 | KCNA3 (0.38) | GPR3KMT2ACA9CA12CA2 | |
| SCHEMBL6995287 | 0.80 | GPR3 (0.39) | GPR3KMT2ACA9CA12CA2 | |
| SCHEMBL9016896 | 0.77 | GPR3 (0.50) | GPR3KMT2ACA9CA12CA2 | |
| SCHEMBL12892713 | 0.77 | GPR3 (0.44) | GPR3KMT2ACA9CA12CA2 | |
| SCHEMBL29700304 | 0.77 | GPR3 (0.50) | GPR3KMT2ACA9CA12CA2 | |
| SCHEMBL2872511 | 0.77 | TYMS (0.50) | GPR3KMT2AKDM4EBCHEUSP2 | |
| SCHEMBL13469962 | 0.74 | MEN1 (0.46) | KMT2ACA9CA12CA2KDM4E | |
| SCHEMBL7633014 | 0.74 | CHEK1 (0.37) | GPR3KMT2ACA9CA12CA2 | |
| SCHEMBL8988312 | 0.74 | ALDH1A1 (0.37) | GPR3KMT2AKDM4ELMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |