Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28492022 | 0.86 | KDM4E (0.47) | L3MBTL1MAPTKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL30006999 | 0.86 | KDM4E (0.47) | L3MBTL1MAPTKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL28001171 | 0.84 | KDM4E (0.50) | L3MBTL1MAPTKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL29056033 | 0.81 | GRM2 (0.47) | RAB9AKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL21292975 | 0.80 | FAAH (0.41) | RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL16598248 | 0.79 | CYP1A2 (0.41) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL8722199 | 0.78 | PARP10 (0.47) | L3MBTL1RAB9AMAPTKDM4ECYP1A2 | |
| SCHEMBL29483170 | 0.77 | KDM4E (0.47) | L3MBTL1RAB9AMAPTKDM4ECYP1A2 | |
| SCHEMBL30006624 | 0.77 | NR3C2 (0.42) | MAPTKDM4ECYP1A2 | |
| SCHEMBL11628722 | 0.77 | L3MBTL1 (0.47) | L3MBTL1RAB9AMAPTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808023-B | Method for preparing 3-aryl isoquinoline derivative | 四川大学 | 2022-10-21 | — | — | CN | disclosed |