Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPM1 | P06748 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23648180 | 1.00 | PABPC1 (0.46) | PABPC1BACE1HTTNT5ECYP2A6 | |
| SCHEMBL20600548 | 0.83 | PABPC1 (0.46) | PABPC1BACE1HTTNT5ECYP2A6 | |
| SCHEMBL26684871 | 0.75 | PABPC1 (0.46) | PABPC1BACE1HTTCYP2A6CYP1A2 | |
| SCHEMBL23535737 | 0.75 | PABPC1 (0.46) | PABPC1BACE1HTTCYP2A6CYP1A2 | |
| SCHEMBL789486 | 0.72 | BACE1 (0.64) | PABPC1BACE1HTTNT5ECYP2A6 | |
| SCHEMBL4347785 | 0.72 | BACE1 (0.58) | PABPC1BACE1HTTNT5ECYP2A6 | |
| SCHEMBL29768297 | 0.72 | BACE1 (0.58) | PABPC1BACE1HTTNT5ECYP2A6 | |
| SCHEMBL2781561 | 0.71 | KDM4E (0.50) | CYP1A2KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL11120969 | 0.71 | PABPC1 (0.60) | PABPC1BACE1HTTNT5ECYP1A2 | |
| SCHEMBL30259059 | 0.71 | PABPC1 (0.60) | PABPC1BACE1HTTNT5ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076449-A1 | PYRIDAZINE AND 1,2,4-TRIAZINE DERIVATIVES AS FGFR KINASE INHIBITORS | Beta Pharma, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |