Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPM1 | P06748 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120969 | 1.00 | PABPC1 (0.60) | PABPC1HTTPIK3CGNT5EPIK3R1 | |
| SCHEMBL11251348 | 0.78 | PIK3CG (0.64) | PIK3CGPIK3R1PIK3CABACE1CYP1A2 | |
| SCHEMBL31530744 | 0.76 | TDP1 (0.50) | PABPC1HTTNT5EPIK3R1PIK3CA | |
| SCHEMBL404395 | 0.76 | TDP1 (0.50) | PABPC1HTTNT5EPIK3R1PIK3CA | |
| SCHEMBL10956299 | 0.75 | PABPC1 (1.00) | PABPC1HTTPIK3CGPIK3R1PIK3CA | |
| SCHEMBL11600471 | 0.75 | PIK3CG (0.41) | PABPC1HTTPIK3CG | |
| SCHEMBL28634341 | 0.74 | PABPC1 (0.58) | PABPC1HTTPIK3R1PIK3CABACE1 | |
| SCHEMBL483060 | 0.74 | PABPC1 (0.58) | PABPC1HTTPIK3R1PIK3CABACE1 | |
| SCHEMBL30179258 | 0.74 | PABPC1 (0.58) | PABPC1HTTPIK3R1PIK3CABACE1 | |
| SCHEMBL23648180 | 0.71 | PABPC1 (0.46) | PABPC1HTTPIK3CGNT5EBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019912-A9 | BENZOTRIAZINE DIOXIDE AND PHARMACEUTICAL COMPOSITION THEREOF | 杭州瑞臻医药有限公司 | 2023-06-01 | — | — | WO | disclosed |
| WO-2023019912-A1 | BENZOTRIAZINE DIOXIDE AND PHARMACEUTICAL COMPOSITION THEREOF | 杭州瑞臻医药有限公司 | 2023-02-23 | — | — | WO | disclosed |