Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535558 | 1.00 | KCNH2 (0.56) | KCNH2CHEK1KDRPIK3CAMKNK1 | |
| SCHEMBL26179021 | 0.86 | CHEK1 (0.50) | KCNH2CHEK1KDRPIK3CAMKNK1 | |
| SCHEMBL26178954 | 0.85 | FLT3 (0.53) | KCNH2CHEK1KDRMKNK1MKNK2 | |
| SCHEMBL15287989 | 0.85 | KDR (0.57) | KCNH2CHEK1KDRPIK3CAMKNK1 | |
| SCHEMBL30217979 | 0.82 | CHEK1 (0.51) | KCNH2CHEK1KDRPIK3CAMKNK1 | |
| SCHEMBL30006563 | 0.81 | TGFBR1 (0.50) | KCNH2CHEK1MKNK1MKNK2DYRK3 | |
| SCHEMBL23535570 | 0.81 | TGFBR1 (0.50) | KCNH2CHEK1MKNK1MKNK2DYRK3 | |
| SCHEMBL73445 | 0.78 | MIF (0.60) | CHEK1KDRPIK3CADYRK3CCNT1 | |
| SCHEMBL23535590 | 0.77 | KCNH2 (0.51) | KCNH2KDRPIK3CAMKNK1MKNK2 | |
| SCHEMBL13336369 | 0.77 | KDR (0.75) | KDRDYRK3CCNT1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |