Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535570 | 1.00 | TGFBR1 (0.50) | TGFBR1MAP4K4KCNH2DYRK3CCNT1 | |
| SCHEMBL23535558 | 0.81 | KCNH2 (0.56) | MAP4K4KCNH2DYRK3CCNT1CCNA2 | |
| SCHEMBL30006817 | 0.81 | KCNH2 (0.56) | MAP4K4KCNH2DYRK3CCNT1CCNA2 | |
| SCHEMBL23105028 | 0.81 | TGFBR1 (0.57) | TGFBR1KCNH2CCNT1CDK9 | |
| SCHEMBL23535618 | 0.80 | TGFBR1 (0.42) | TGFBR1MAP4K4 | |
| SCHEMBL30006850 | 0.80 | TGFBR1 (0.42) | TGFBR1MAP4K4 | |
| SCHEMBL26178954 | 0.78 | FLT3 (0.53) | MAP4K4KCNH2DYRK3CCNT1CCNA2 | |
| SCHEMBL23535608 | 0.77 | IKBKB (0.45) | TGFBR1KCNH2FYNTGFBR2 | |
| SCHEMBL17754846 | 0.76 | TGFBR1 (0.43) | TGFBR1 | |
| SCHEMBL23535607 | 0.75 | FYN (0.55) | DYRK3CCNT1CCNA2CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |