Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 4/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687293 | 1.00 | POLB (0.34) | POLBSSTR5ENPP2SYKMAPK14 | |
| SCHEMBL30007202 | 1.00 | POLB (0.34) | POLBSSTR5ENPP2SYKMAPK14 | |
| SCHEMBL30006951 | 0.94 | CFTR (0.33) | SSTR5ENPP2MAPK14CYP2C9MCHR1 | |
| SCHEMBL25232424 | 0.94 | CFTR (0.33) | SSTR5ENPP2MAPK14CYP2C9MCHR1 | |
| SCHEMBL25687289 | 0.94 | CFTR (0.33) | SSTR5ENPP2MAPK14CYP2C9MCHR1 | |
| SCHEMBL25687227 | 0.93 | POLB (0.35) | POLBSSTR5SYKEPHX2 | |
| SCHEMBL23958737 | 0.93 | POLB (0.35) | POLBSSTR5SYKEPHX2 | |
| SCHEMBL23958645 | 0.91 | GABRA5 (0.36) | ENPP2MAPK14CYP2C9EPHX2CNR1 | |
| SCHEMBL30007230 | 0.91 | GABRA5 (0.36) | ENPP2MAPK14CYP2C9EPHX2CNR1 | |
| SCHEMBL25686195 | 0.91 | GABRA5 (0.36) | ENPP2MAPK14CYP2C9EPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |