⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27093801 | 1.00 | — | — | |
| SCHEMBL30878232 | 0.75 | PIK3CD (0.32) | — | |
| SCHEMBL30754558 | 0.73 | TOP1 (0.32) | — | |
| SCHEMBL27093848 | 0.73 | TOP1 (0.32) | — | |
| SCHEMBL21494875 | 0.73 | KRAS (0.33) | — | |
| SCHEMBL24800366 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL31115646 | 0.73 | — | — | |
| SCHEMBL29863061 | 0.73 | KRAS (0.33) | — | |
| SCHEMBL31115650 | 0.73 | TDP1 (0.36) | — | |
| SCHEMBL21494905 | 0.71 | KRAS (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602049-A1 | SOS1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-08-20 | — | — | EP | disclosed |
| EP-4322962-A1 | PHOSPHORUS DERIVATIVES AS NOVEL SOS1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2024-02-21 | — | — | EP | disclosed |
| CN-117500507-A | Phosphorus derivatives as novel SOS1 inhibitors | 拜耳公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022219035-A1 | PHOSPHORUS DERIVATIVES AS NOVEL SOS1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-10-20 | — | — | WO | disclosed |