Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26687939 | 1.00 | NR1H4 (0.53) | NR1H4EPHX2MAPTALDH1A1LMNA | |
| SCHEMBL31745865 | 0.84 | NR3C2 (0.50) | NR1H4MAPTALDH1A1LMNAGAA | |
| SCHEMBL735333 | 0.84 | MMP2 (0.53) | EPHX2ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL943656 | 0.84 | MMP2 (0.53) | EPHX2ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9153423 | 0.82 | CYP2D6 (0.40) | NR1H4EPHX2MAPTALDH1A1LMNA | |
| SCHEMBL11197943 | 0.82 | NR1H4 (0.50) | NR1H4EPHX2MAPTALDH1A1NPC1 | |
| SCHEMBL11197937 | 0.82 | NR1H4 (0.50) | NR1H4EPHX2MAPTALDH1A1NPC1 | |
| SCHEMBL6495352 | 0.80 | SMN1; SMN2 (0.57) | LMNANPSR1SMN1; SMN2HTT | |
| SCHEMBL6495349 | 0.80 | SMN1; SMN2 (0.57) | LMNANPSR1SMN1; SMN2HTT | |
| SCHEMBL7089012 | 0.79 | CA12 (0.47) | NR1H4MAPTALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240758-A1 | COMPOSITIONS AND METHODS FOR MODULATING GENE EXPRESSION | ENTRADA THERAPEUTICS, INC. (US) | 2022-11-17 | — | — | WO | claimed |
| CN-117362188-B | Synthesis method of alpha-substituted deuterated amino acid ester | 广州医科大学 | 2025-05-20 | — | — | CN | disclosed |
| EP-4522221-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS | Entrada Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| CN-117362188-A | Synthesis method of alpha-substituted deuterated amino acid ester | 广州医科大学 | 2024-01-09 | — | — | CN | disclosed |
| WO-2023219933-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS | ENTRADA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |