Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25686856 | 1.00 | SLC34A1 (0.34) | SLC34A1ADORA2AADORA2BADORA1DHODH | |
| SCHEMBL23958662 | 0.90 | ADORA2A (0.33) | SLC34A1ADORA2AADORA2BADORA1CFTR | |
| SCHEMBL30006948 | 0.90 | ADORA2A (0.33) | SLC34A1ADORA2AADORA2BADORA1CFTR | |
| SCHEMBL25423458 | 0.76 | CFTR (0.37) | CFTRMAPK14ALDH1A1PKM | |
| SCHEMBL30007134 | 0.75 | SLC34A1 (0.36) | SLC34A1ADORA2AADORA2BADORA1DHODH | |
| SCHEMBL25686851 | 0.75 | SLC34A1 (0.36) | SLC34A1ADORA2AADORA2BADORA1DHODH | |
| SCHEMBL26727261 | 0.74 | CFTR (0.34) | ADORA2AADORA2BADORA1CFTRCYP19A1 | |
| SCHEMBL30006977 | 0.72 | SLC34A1 (0.35) | SLC34A1CFTRCYP19A1MAPK14NR3C1 | |
| SCHEMBL25686861 | 0.72 | SLC34A1 (0.35) | SLC34A1CFTRCYP19A1MAPK14NR3C1 | |
| SCHEMBL23958637 | 0.69 | SLC34A1 (0.35) | SLC34A1ADORA2AADORA2BADORA1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |