Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 5/20 | 0.36 |
| ▸ | DHODH | Q02127 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25686851 | 1.00 | SLC34A1 (0.36) | SLC34A1DHODHALDH1A1PKMMAPK14 | |
| SCHEMBL23958637 | 0.88 | SLC34A1 (0.35) | SLC34A1DHODHALDH1A1PKMMAPK14 | |
| SCHEMBL30007279 | 0.88 | SLC34A1 (0.35) | SLC34A1DHODHALDH1A1PKMMAPK14 | |
| SCHEMBL30007400 | 0.81 | SLC34A1 (0.37) | SLC34A1DHODHMAPK14ADORA3ADORA2A | |
| SCHEMBL23930104 | 0.81 | SLC34A1 (0.37) | SLC34A1DHODHMAPK14ADORA3ADORA2A | |
| SCHEMBL23958967 | 0.77 | CDK8 (0.41) | ALDH1A1PKM | |
| SCHEMBL25686724 | 0.76 | SCN9A (0.35) | ALDH1A1PKMMAPK14BRAFFAAH | |
| SCHEMBL30007397 | 0.75 | SLC34A1 (0.34) | SLC34A1DHODHALDH1A1PKMMAPK14 | |
| SCHEMBL25686856 | 0.75 | SLC34A1 (0.34) | SLC34A1DHODHALDH1A1PKMMAPK14 | |
| SCHEMBL25236947 | 0.74 | ALDH1A1 (0.39) | DHODHALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |