Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930104 | 1.00 | SLC34A1 (0.37) | SLC34A1MAPK14MAPK10BRAFCDK8 | |
| SCHEMBL23958731 | 0.90 | L3MBTL1 (0.43) | SLC34A1CDK8CDK5CLK4CNR1 | |
| SCHEMBL30007279 | 0.89 | SLC34A1 (0.35) | SLC34A1MAPK14MAPK10BRAFCDK8 | |
| SCHEMBL23958637 | 0.89 | SLC34A1 (0.35) | SLC34A1MAPK14MAPK10BRAFCDK8 | |
| SCHEMBL23958949 | 0.81 | CFTR (0.35) | SLC34A1BRAFCYP11B1CYP11B2KDM5B | |
| SCHEMBL30007134 | 0.81 | SLC34A1 (0.36) | SLC34A1MAPK14BRAFCYP11B1CYP11B2 | |
| SCHEMBL25686851 | 0.81 | SLC34A1 (0.36) | SLC34A1MAPK14BRAFCYP11B1CYP11B2 | |
| SCHEMBL23958967 | 0.78 | CDK8 (0.41) | CDK8CDK5CLK4SMN1; SMN2 | |
| SCHEMBL25686724 | 0.77 | SCN9A (0.35) | MAPK14BRAFPTGDR2CNR2FAAH | |
| SCHEMBL23958695 | 0.77 | CFTR (0.34) | SLC34A1CYP11B1CYP11B2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |