Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | GPR39 | O43194 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101302 | 0.77 | GAA (0.51) | ALDH1A1POLBROCK2 | |
| SCHEMBL24625406 | 0.76 | KDM4E (0.53) | ALDH1A1POLB | |
| SCHEMBL30754559 | 0.76 | KDM5A (0.56) | ALDH1A1POLBHCAR2KDM5AKDM4C | |
| SCHEMBL11782173 | 0.73 | HCAR2 (0.43) | ALDH1A1POLBHCAR2 | |
| SCHEMBL25098508 | 0.73 | HCAR2 (0.37) | ALDH1A1POLBHCAR2ROCK1 | |
| SCHEMBL24791096 | 0.71 | GRIN2D (0.44) | ALDH1A1POLB | |
| SCHEMBL24792669 | 0.70 | KDM4E (0.52) | ALDH1A1POLB | |
| SCHEMBL30170779 | 0.70 | KDM4E (0.52) | ALDH1A1POLB | |
| SCHEMBL22101792 | 0.68 | PIM1 (0.38) | HCAR2 | |
| SCHEMBL24792663 | 0.66 | GUSB (0.43) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894893-A | Sulfone substituted pyrido [3,4-D ] pyrimidine derivatives for the treatment of cancer | 拜耳公司 | 2025-04-25 | — | — | CN | disclosed |
| EP-4322962-A1 | PHOSPHORUS DERIVATIVES AS NOVEL SOS1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2024-02-21 | — | — | EP | disclosed |
| CN-117500507-A | Phosphorus derivatives as novel SOS1 inhibitors | 拜耳公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022219035-A1 | PHOSPHORUS DERIVATIVES AS NOVEL SOS1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-10-20 | — | — | WO | disclosed |