Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954318 | 0.79 | TUBB4A (0.52) | GAAMAPTNPSR1RXFP1TUBB4A | |
| SCHEMBL27093935 | 0.77 | ALDH1A1 (0.39) | ALDH1A1POLBROCK2 | |
| SCHEMBL30007553 | 0.77 | ALDH1A1 (0.39) | ALDH1A1POLBROCK2 | |
| SCHEMBL856487 | 0.77 | ALDH1A1 (0.58) | MAPTNPSR1HTTALDH1A1POLB | |
| SCHEMBL3115005 | 0.76 | TYMS (0.72) | GAAMAPTNPSR1RXFP1TUBB4A | |
| SCHEMBL29900526 | 0.76 | TYMS (0.72) | GAAMAPTNPSR1RXFP1TUBB4A | |
| SCHEMBL3424900 | 0.76 | TUBB4A (0.55) | GAAMAPTNPSR1RXFP1TUBB4A | |
| SCHEMBL1396365 | 0.75 | ALDH1A1 (0.62) | GAAMAPTNPSR1RXFP1TUBB4A | |
| SCHEMBL22101792 | 0.75 | PIM1 (0.38) | MAPTRXFP1PIM1PIM3HTT | |
| SCHEMBL10313788 | 0.73 | ALDH1A1 (0.58) | HTTCSNK2A1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |