Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 12/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187376 | 1.00 | LTA4H (0.45) | LTA4HMAOBPDE4BMAPTTDP1 | |
| SCHEMBL12960368 | 0.86 | CNR2 (0.40) | MAOBNPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL20187352 | 0.80 | KMT2A (0.39) | MAOBPDE4BMAPTTDP1L3MBTL1 | |
| SCHEMBL2761859 | 0.76 | MAOB (0.67) | MAOBMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL2868883 | 0.75 | TSHR (0.38) | MAOBMAPTTDP1L3MBTL1NPC1 | |
| SCHEMBL12116974 | 0.74 | MAOB (0.43) | MAOBMAPTTDP1L3MBTL1NPC1 | |
| SCHEMBL1165753 | 0.74 | TSHR (0.36) | MAOBTDP1L3MBTL1ALDH1A1GLA | |
| SCHEMBL14879974 | 0.73 | AKR1B1 (0.48) | MAPTTDP1ALDH1A1LMNA | |
| SCHEMBL3029678 | 0.73 | MAOB (0.43) | MAOBTDP1L3MBTL1MAOA | |
| SCHEMBL4956149 | 0.73 | CYP3A4 (0.52) | MAOBNPC1ALDH1A1RAB9AGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234638-B | Heteroaryl phenoxy benzamide KAPPA opioid ligands | 辉瑞大药厂 | 2022-10-21 | — | — | CN | disclosed |