Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | ATR | Q13535 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007739 | 0.71 | NAMPT (0.43) | CNR1ATR | |
| SCHEMBL30008206 | 0.67 | CLK1 (0.43) | ATR | |
| SCHEMBL30007248 | 0.67 | ATR (0.40) | CNR2ATR | |
| SCHEMBL16804367 | 0.63 | HDAC6 (0.53) | GLO1 | |
| SCHEMBL18852659 | 0.63 | HDAC8 (0.42) | CNR2CNR1GLO1 | |
| SCHEMBL18108895 | 0.63 | HDAC6 (0.58) | — | |
| SCHEMBL18108862 | 0.62 | HDAC6 (0.57) | GLO1 | |
| SCHEMBL16804239 | 0.61 | CYP11B2 (0.44) | GLO1 | |
| SCHEMBL10060466 | 0.60 | CA12 (0.46) | — | |
| SCHEMBL18125645 | 0.60 | HDAC6 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237922-A1 | ANTITUMOR COMPOUNDS BASED ON NITROGEN HETEROCYCLES AND USE THEREOF AS MEDICAMENTS | FAKULTNI NEMOCNICE HRADEC KRALOVE (CZ) | 2022-11-17 | — | — | WO | claimed |