Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 2/20 | 0.66 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.66 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.66 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.66 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.66 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.66 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18563067 | 1.00 | CALM1 (0.66) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20682611 | 0.93 | POLB (0.68) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL9089602 | 0.88 | CALM1 (0.64) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL30008021 | 0.84 | TUBB4A (0.63) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL29934781 | 0.84 | TUBB4A (0.63) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL29449679 | 0.84 | TUBB4A (0.63) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL18546196 | 0.84 | TUBB4A (0.63) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL16372690 | 0.83 | AKR1B1 (0.71) | AKR1B1PTPN1ALOX5NOS2KDM4E | |
| SCHEMBL20179761 | 0.82 | CALM1 (0.57) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL30834896 | 0.81 | CALM1 (0.68) | CALM1GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022236789-A1 | EXTRACT OF DENDROBIUM SINENSE, DENDROBIUM DENSIFLORUM, OR DENDROBIUM BENSONIAE, AND APPLICATION OF MAIN COMPONENTS THEREOF AS ANTI-INFLAMMATORY FORMULATION | 中国热带农业科学院热带生物技术研究所 | 2022-11-17 | — | — | WO | claimed |
| WO-2022236789-A1 | EXTRACT OF DENDROBIUM SINENSE, DENDROBIUM DENSIFLORUM, OR DENDROBIUM BENSONIAE, AND APPLICATION OF MAIN COMPONENTS THEREOF AS ANTI-INFLAMMATORY FORMULATION | 中国热带农业科学院热带生物技术研究所 | 2022-11-17 | — | — | WO | disclosed |