Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3001790 | 0.91 | KDM4E (0.40) | MAPTSMN1; SMN2THRBKDM4EL3MBTL1 | |
| SCHEMBL2997500 | 0.91 | KDM4E (0.40) | MAPTSMN1; SMN2THRBKDM4EL3MBTL1 | |
| SCHEMBL3001004 | 0.90 | KDM4E (0.39) | MAPTSMN1; SMN2THRBKDM4EL3MBTL1 | |
| SCHEMBL3006452 | 0.90 | KDM4E (0.39) | MAPTSMN1; SMN2THRBKDM4EL3MBTL1 | |
| SCHEMBL3008051 | 0.90 | KDM4E (0.39) | MAPTSMN1; SMN2THRBKDM4EL3MBTL1 | |
| SCHEMBL3006446 | 0.90 | PTGES (0.44) | KMT2AMEN1PTGESPPARGPPARA | |
| SCHEMBL4698563 | 0.89 | PTGES (0.39) | MAPTSMN1; SMN2KDM4EL3MBTL1PTGES | |
| SCHEMBL334166 | 0.88 | PTGES (0.40) | MAPTSMN1; SMN2THRBKDM4EL3MBTL1 | |
| SCHEMBL3010510 | 0.88 | PTGES (0.38) | MAPTSMN1; SMN2THRBKDM4EL3MBTL1 | |
| SCHEMBL4700284 | 0.88 | PTGES (0.37) | KMT2AMEN1MAPTSMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, TPH1 | KMT2A 3808/4885MEN1 2218/4885MAPT 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.