Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009126 | 0.74 | PLK4 (0.45) | PLK4PAK4 | |
| SCHEMBL30009075 | 0.71 | — | — | |
| SCHEMBL61883 | 0.64 | PLK4 (0.53) | PLK4PAK4 | |
| SCHEMBL29700716 | 0.63 | PRKCI (0.44) | PAK4 | |
| SCHEMBL3655551 | 0.63 | DHFR (0.35) | — | |
| SCHEMBL12398424 | 0.60 | PLK4 (0.36) | PLK4PAK4 | |
| SCHEMBL31439112 | 0.60 | NOS1 (0.37) | PLK4PAK4 | |
| SCHEMBL2266999 | 0.60 | PLK4 (0.45) | PLK4PAK4 | |
| SCHEMBL341706 | 0.60 | ADORA2A (0.47) | PLK4PAK4 | |
| SCHEMBL560806 | 0.60 | RET (0.52) | PLK4PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |