Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415059 | 1.00 | ADRB1 (0.44) | ADRB1ABL1KMT2AMAPTALDH1A1 | |
| SCHEMBL13260410 | 0.79 | MAOB (0.54) | ADRB1ABL1MAPTALDH1A1GAA | |
| SCHEMBL4807893 | 0.76 | KMT2A (0.47) | ABL1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL20285407 | 0.76 | MEN1 (0.41) | ABL1KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL30451094 | 0.71 | KDM4E (0.42) | MAPTALDH1A1KDM4ENOTUMTP53 | |
| SCHEMBL7864461 | 0.70 | ABL1 (0.59) | ABL1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7719911 | 0.69 | ABL1 (0.77) | ABL1KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL28398096 | 0.68 | KMT2A (0.41) | ADRB1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11479045 | 0.67 | KMT2A (0.59) | ADRB1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL24140572 | 0.66 | ADRB1 (0.68) | ADRB1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021928-B | Eltrombopag intermediate, preparation method and application thereof | 常州制药厂有限公司 | 2022-11-18 | — | — | CN | disclosed |