Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20405080 | 0.80 | ABL1 (0.66) | ABL1 | |
| SCHEMBL7719911 | 0.77 | ABL1 (0.77) | KMT2AABL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31415059 | 0.76 | ADRB1 (0.44) | KMT2AABL1ALDH1A1MAPTMEN1 | |
| SCHEMBL30008614 | 0.76 | ADRB1 (0.44) | KMT2AABL1ALDH1A1MAPTMEN1 | |
| SCHEMBL31065089 | 0.74 | MAOB (0.51) | KMT2AALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL14107040 | 0.72 | KMT2A (0.69) | KMT2AALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8264511 | 0.70 | MAPT (0.68) | KMT2AALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7816315 | 0.69 | ALDH1A1 (0.56) | KMT2AALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL10053481 | 0.68 | PKM (0.48) | KMT2AALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL30228205 | 0.68 | MEN1 (0.69) | KMT2AALDH1A1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103866-A1 | SYNTHESIS OF INDOLES | MICROBIA, INC. (US) | 2008-08-28 | — | — | WO | disclosed |