Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.59 |
| ▸ | REN | P00797 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277740 | 0.87 | CASP1 (0.75) | CASP1RENBACE1BACE2OPRD1 | |
| SCHEMBL4349143 | 0.87 | CASP1 (0.75) | CASP1RENBACE1BACE2OPRD1 | |
| SCHEMBL5689425 | 0.84 | CASP1 (0.49) | CASP1RENBACE1BACE2OPRD1 | |
| SCHEMBL7197343 | 0.82 | CASP1 (0.65) | CASP1BACE1BACE2OPRD1CASP3 | |
| SCHEMBL15462621 | 0.82 | CASP3 (0.61) | CASP1RENCASP3CASP7CTSS | |
| SCHEMBL20052370 | 0.82 | CASP3 (0.61) | CASP1RENCASP3CASP7CTSS | |
| SCHEMBL7275856 | 0.81 | CASP1 (0.49) | CASP1RENBACE1BACE2OPRD1 | |
| SCHEMBL7284988 | 0.80 | CASP1 (0.49) | CASP1RENBACE1BACE2OPRD1 | |
| SCHEMBL7287204 | 0.80 | CASP1 (0.49) | CASP1RENBACE1BACE2OPRD1 | |
| SCHEMBL7275894 | 0.80 | BACE1 (0.50) | CASP1RENBACE1BACE2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11525155-B2 | Stabilisation of biological samples | QIAGEN GMBH (DE) | 2022-12-13 | — | — | US | disclosed |