SCHEMBL30008731

SCHEMBL30008731

O=S(=O)(Nc1ccc(-c2ncnc3[nH]ccc23)cc1)c1ccc(F)cc1

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIT P10721 18/20 0.69
IKBKB O14920 1/20 0.63
CHUK O15111 1/20 0.63
EGFR P00533 1/20 0.55
AURKB Q96GD4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009044 0.88 KIT (0.67) KITIKBKBCHUKEGFRAURKB
SCHEMBL30009483 0.88 KIT (0.67) KITIKBKBCHUKEGFRAURKB
SCHEMBL30009814 0.87 KIT (0.70) KITIKBKBCHUK
SCHEMBL30009296 0.86 KIT (0.60) KITIKBKBCHUKEGFRAURKB
SCHEMBL15664603 0.81 KIT (1.00) KIT
SCHEMBL15664595 0.81 KIT (1.00) KIT
SCHEMBL30009257 0.81 IKBKB (0.66) IKBKBCHUK
SCHEMBL24805256 0.81 IKBKB (0.70) KITIKBKBCHUKEGFRAURKB
SCHEMBL15664057 0.81 KIT (1.00) KIT
SCHEMBL30009111 0.79 ROCK2 (0.60) KITIKBKBCHUK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor MAP3K20, MAP3K15, MAP3K1 KIT 3668/4885IKBKB 294/4885CHUK 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.