Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.60 |
| ▸ | CIT | O14578 | 1/20 | 0.58 |
| ▸ | JAK1 | P23458 | 3/20 | 0.58 |
| ▸ | JAK2 | O60674 | 2/20 | 0.54 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.53 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.53 |
| ▸ | JAK3 | P52333 | 5/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 3/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009600 | 0.88 | LIMK1 (0.61) | ROCK2LIMK1CYP3A4CYP3A5CIT | |
| SCHEMBL28871098 | 0.84 | CIT (0.63) | ROCK2LIMK1CYP3A4CYP3A5CIT | |
| SCHEMBL30009442 | 0.82 | CIT (0.62) | ROCK2LIMK1CYP3A4CYP3A5CIT | |
| SCHEMBL30008743 | 0.81 | KIT (0.57) | ROCK2LIMK1CYP3A4CYP3A5CIT | |
| SCHEMBL30009371 | 0.80 | CIT (0.63) | ROCK2CITIKBKBCHUKAURKA | |
| SCHEMBL4791969 | 0.80 | CIT (0.63) | ROCK2CITIKBKBCHUKAURKA | |
| SCHEMBL30009157 | 0.80 | BTK (0.55) | LIMK1CITJAK2IKBKBCHUK | |
| SCHEMBL28345572 | 0.80 | JAK3 (0.74) | ROCK2LIMK1CYP3A4CYP3A5CIT | |
| SCHEMBL30008731 | 0.79 | KIT (0.69) | IKBKBCHUKKIT | |
| SCHEMBL30009617 | 0.79 | JAK1 (0.63) | ROCK2LIMK1CYP3A4CYP3A5CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | ROCK2 466/4885LIMK1 591/4885CYP3A4 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.