Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 4/20 | 0.61 |
| ▸ | JAK1 | P23458 | 3/20 | 0.61 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.61 |
| ▸ | JAK3 | P52333 | 6/20 | 0.56 |
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.56 |
| ▸ | FLT1 | P17948 | 3/20 | 0.56 |
| ▸ | JAK2 | O60674 | 3/20 | 0.56 |
| ▸ | BTK | Q06187 | 3/20 | 0.56 |
| ▸ | AURKA | O14965 | 2/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.56 |
| ▸ | PAK4 | O96013 | 2/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.56 |
| ▸ | CSF1R | P07333 | 2/20 | 0.56 |
| ▸ | RET | P07949 | 2/20 | 0.56 |
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009111 | 0.88 | ROCK2 (0.60) | LIMK1JAK1ROCK2CYP3A4CYP3A5 | |
| SCHEMBL28871098 | 0.80 | CIT (0.63) | LIMK1JAK1ROCK2CYP3A4CYP3A5 | |
| SCHEMBL30009442 | 0.79 | CIT (0.62) | LIMK1JAK1ROCK2CYP3A4CYP3A5 | |
| SCHEMBL30008743 | 0.78 | KIT (0.57) | LIMK1JAK1ROCK2CYP3A4CYP3A5 | |
| SCHEMBL30009814 | 0.77 | KIT (0.70) | JAK3KDRFGFR1FLT1JAK2 | |
| SCHEMBL20917967 | 0.76 | JAK1 (1.00) | JAK1 | |
| SCHEMBL3127395 | 0.76 | ROCK2 (1.00) | LIMK1ROCK2CYP3A4CYP3A5JAK3 | |
| SCHEMBL28345572 | 0.76 | JAK3 (0.74) | LIMK1JAK1ROCK2CYP3A4CYP3A5 | |
| SCHEMBL30009617 | 0.75 | JAK1 (0.63) | LIMK1JAK1ROCK2CYP3A4CYP3A5 | |
| SCHEMBL29291567 | 0.75 | CIT (0.57) | LIMK1JAK1ROCK2CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | LIMK1 591/4885JAK1 83/4885ROCK2 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.