SCHEMBL30009510

SCHEMBL30009510

CC1(C)OCC(COc2cc(F)cc([C@H]3CCCN3c3ccn4ncc(C(=O)NC5CC5)c4n3)c2)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NTRK1 P04629 20/20 1.00
▸ JAK2 O60674 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950685 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL945616 0.91 NTRK1 (1.00) NTRK1JAK2
SCHEMBL19547400 0.90 NTRK1 (0.82) NTRK1JAK2
SCHEMBL951822 0.88 NTRK1 (1.00) NTRK1JAK2
SCHEMBL4295722 0.86 NTRK1 (0.76) NTRK1JAK2
SCHEMBL19547403 0.85 JAK2 (0.83) NTRK1JAK2
SCHEMBL2694949 0.85 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2694945 0.85 NTRK1 (1.00) NTRK1JAK2
SCHEMBL19987903 0.85 NTRK1 (0.89) NTRK1JAK2
SCHEMBL30009477 0.82 NTRK1 (1.00) NTRK1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945378-B Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof 休斯敦大学体系 2024-11-19 — — CN disclosed
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 — — EP disclosed
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