Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20742322 | 0.87 | CA1 (0.33) | CA1CA2ALDH1A1MCL1TRIM24 | |
| SCHEMBL31035610 | 0.81 | CA1 (0.40) | CA1CA2ALDH1A1TRIM24TYR | |
| SCHEMBL25594012 | 0.77 | ERN1 (0.49) | CA1CA2ALDH1A1TRIM24TYR | |
| SCHEMBL1135193 | 0.77 | ALDH1A1 (0.50) | CA1CA2ALDH1A1TRIM24TYR | |
| SCHEMBL2298163 | 0.76 | LPL (0.39) | CA1CA2CA9KMT2ALPL | |
| SCHEMBL29729025 | 0.75 | CA1 (0.59) | CA1CA2ALDH1A1MCL1TRIM24 | |
| SCHEMBL3345839 | 0.75 | CA1 (0.59) | CA1CA2ALDH1A1MCL1TRIM24 | |
| SCHEMBL28867630 | 0.75 | CA1 (0.37) | CA1CA2ALDH1A1ERN1SRC | |
| SCHEMBL29793277 | 0.73 | LPL (0.38) | ALDH1A1MCL1KMT2ALPLLIPG | |
| SCHEMBL3040438 | 0.73 | LPL (0.38) | ALDH1A1MCL1KMT2ALPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041724-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | Novartis AG (CH) | 2022-08-17 | — | — | EP | disclosed |