Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686865 | 0.99 | NR1H4 (0.44) | KMT2ANR1H4GAAALPLSLC22A12 | |
| SCHEMBL30549039 | 0.85 | ALPL (0.47) | NR1H4GAAALPLSLC22A12SLC40A1 | |
| SCHEMBL25248899 | 0.85 | ALPL (0.49) | GAAALPLSLC22A12SLC40A1PTGER4 | |
| SCHEMBL9522813 | 0.82 | GAA (0.42) | KMT2AGAAKDM4EATMTSHR | |
| SCHEMBL30009742 | 0.80 | HIF1A (0.51) | KMT2ANR1H4GAASLC22A12MEN1 | |
| SCHEMBL11851628 | 0.78 | GAA (0.49) | GAATSHRSMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL9852809 | 0.77 | ALPL (0.47) | NR1H4ALPLSLC22A12SLC40A1PTGER4 | |
| SCHEMBL9074962 | 0.77 | CA12 (0.58) | KMT2AGAAATMTSHRMEN1 | |
| SCHEMBL14676386 | 0.76 | ALPL (0.46) | GAAALPLSLC22A12SLC40A1MRGPRX1 | |
| SCHEMBL7021598 | 0.76 | GAA (0.48) | GAAPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732711-A | CORRESPONDING SULFONYLISOLYANATE AND THIOISOCYANATE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-22 | — | — | US | disclosed |