SCHEMBL30009787

SCHEMBL30009787

CCOC(=O)Cc1ccccc1OCc1cc(-c2cccc(CN)c2)c2occc2c1OCc1ccncc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CFD P00746 17/20 0.50
F11 P03951 3/20 0.45
TPSB2 P20231 3/20 0.45
PLG P00747 1/20 0.45
PLAU P00749 1/20 0.45
KLKB1 P03952 1/20 0.45
F7 P08709 1/20 0.45
TBXAS1 P24557 1/20 0.37
PTGER1 P34995 2/20 0.36
PTGER4 P35408 2/20 0.36
PTGER3 P43115 2/20 0.36
PTGER2 P43116 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23217521 1.00 CFD (0.50) CFDF11TPSB2PLGPLAU
SCHEMBL30009841 0.90 CFD (0.59) CFDF11TPSB2PLGPLAU
SCHEMBL23217761 0.90 CFD (0.59) CFDF11TPSB2PLGPLAU
SCHEMBL30010309 0.89 CFD (0.51) CFDF11TPSB2PLGPLAU
SCHEMBL23217268 0.89 CFD (0.51) CFDF11TPSB2PLGPLAU
SCHEMBL23217592 0.89 CFD (0.50) CFDF11TPSB2PLGPLAU
SCHEMBL30010535 0.89 CFD (0.50) CFDF11TPSB2PLGPLAU
SCHEMBL23217860 0.89 CFD (0.51) CFDF11TPSB2PLGPLAU
SCHEMBL23217477 0.87 CFD (0.49) CFDF11TPSB2PLGPLAU
SCHEMBL30010482 0.87 CFD (0.49) CFDF11TPSB2PLGPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4041717-A1 ORAL COMPLEMENT FACTOR D INHIBITORS Biocryst Pharmaceuticals, Inc. (US) 2022-08-17 EP disclosed