Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3000796 | 0.84 | MAP4K1 (0.35) | MCHR1MAP4K1HRH3KCNH2PIM2 | |
| SCHEMBL3002020 | 0.84 | MCHR1 (0.34) | MCHR1DGAT1HRH3KCNH2ADORA2A | |
| SCHEMBL3006194 | 0.81 | MAP4K1 (0.36) | MCHR1MAP4K1HRH3KCNH2PIM2 | |
| SCHEMBL3576199 | 0.80 | PPARG (0.40) | MCHR1DGAT1KCNH2ADORA2APPARD | |
| SCHEMBL3573981 | 0.77 | PPARG (0.41) | DGAT1KCNH2ADORA2APPARDPPARA | |
| SCHEMBL3569793 | 0.77 | GCK (0.40) | MCHR1DGAT1KCNH2ADORA2APPARD | |
| SCHEMBL3012453 | 0.75 | PTGES (0.39) | MCHR1MAP4K1 | |
| SCHEMBL3003503 | 0.73 | PRMT5 (0.34) | MCHR1MAP4K1HRH3KCNH2ADORA2A | |
| SCHEMBL3017912 | 0.73 | PPARA (0.37) | MCHR1DGAT1KCNH2ADORA2APPARD | |
| SCHEMBL3005745 | 0.72 | MCHR1 (0.35) | MCHR1DGAT1HRH3KCNH2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, TPH1 | MCHR1 89/4885MAP4K1 293/4885DGAT1 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.