SCHEMBL30009941

SCHEMBL30009941

O=Cc1cnc(O)nc1O

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
ERN1 O75460 5/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
HSP90AA1 P07900 1/20 0.32
IDO1 P14902 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CCR1 P32246 1/20 0.30
CCR5 P51681 1/20 0.30
CCR8 P51685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14940691 1.00 TRIM24 (0.33) TRIM24TRIM33ERN1KDM4EMEN1
SCHEMBL6691290 0.74 ERN1 (0.38) TRIM24TRIM33ERN1KDM4E
SCHEMBL28062887 0.72 KDM5A (0.33)
SCHEMBL149516 0.67
Water SCHEMBL29599612 0.65
SCHEMBL21993012 0.65
SCHEMBL7186781 0.65 ERN1 (0.43) TRIM24TRIM33ERN1
SCHEMBL11692476 0.65 TRIM24 (0.39) TRIM24TRIM33ERN1KDM4EMEN1
SCHEMBL1420754 0.65
SCHEMBL152156 0.64 HPGD (0.40) KDM4EMEN1KMT2ANPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903250-B Process for preparing 2, 4-dichloro-5-pyrimidinecarbaldehyde and derivatives thereof 安庆博曼生物技术有限公司 2022-11-18 CN claimed
CN-121574134-A Preparation method of treasipril and salt thereof 济南圣泉集团股份有限公司 2026-02-27 CN disclosed
CN-116332859-B Hydrazone compound and preparation method and application thereof 华中师范大学 2025-02-25 CN disclosed
CN-118812424-A Triarylmethane derivative and preparation method and application thereof 重庆文理学院 2024-10-22 CN disclosed
CN-116332859-A Hydrazone compound and preparation method and application thereof 华中师范大学 2023-06-27 CN disclosed
CN-110903250-B Process for preparing 2, 4-dichloro-5-pyrimidinecarbaldehyde and derivatives thereof 安庆博曼生物技术有限公司 2022-11-18 CN disclosed
CN-110903250-B Process for preparing 2, 4-dichloro-5-pyrimidinecarbaldehyde and derivatives thereof 安庆博曼生物技术有限公司 2022-11-18 CN disclosed