SCHEMBL152156

SCHEMBL152156

O=C(O)c1cnc(O)nc1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.40
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38
GABRG1 Q8N1C3 2/20 0.38
GABRG3 Q99928 2/20 0.38
GABRQ Q9UN88 2/20 0.38
KDM4E B2RXH2 7/20 0.37
KMT2A Q03164 3/20 0.37
NAPRT Q6XQN6 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2745045 0.98 HPGD (0.39) HPGDGABRPGABRDGABRA1GABRB1
Hydrochloric Acid SCHEMBL11591950 0.98 HPGD (0.39) HPGDGABRPGABRDGABRA1GABRB1
SCHEMBL11010839 0.82
SCHEMBL20321273 0.80
SCHEMBL10198951 0.80 POLB (0.44) HPGDKDM4EKMT2AALDH1A1TDP1
SCHEMBL16861500 0.80 PARP1 (0.40) HPGDKDM4EALDH1A1TDP1CHEK1
SCHEMBL8546294 0.78 HPGD (0.59) HPGDGABRPGABRDGABRA1GABRB1
SCHEMBL6517817 0.78 GABRP (0.44) HPGDGABRPGABRDGABRA1GABRB1
SCHEMBL8738488 0.78 KEAP1 (0.46) HPGDGABRPGABRDGABRA1GABRB1
SCHEMBL991323 0.78 GABRP (0.44) HPGDGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 563 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037513-A Antibacterial packaging material and preparation method thereof 安徽腾奎新材料有限公司 2026-05-15 CN claimed
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone L'OREAL (FR) 2022-08-02 US claimed
US-11298305-B2 Compositions and methods for improving the appearance of the hair L'OREAL (FR) 2022-04-12 US claimed
CN-111039270-B Flower-shaped zinc phosphate nanoparticle antibacterial material and preparation method and application thereof 天津科技大学 2021-10-08 CN claimed
EP-2988830-B1 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF OREAL (FR) 2021-03-17 EP claimed
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2020-07-02 US claimed
CN-111039270-A Flower-shaped zinc phosphate nanoparticle antibacterial material and preparation method and application thereof 天津科技大学 2020-04-21 CN claimed
EP-2916808-B1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION OREAL (FR) 2019-06-26 EP claimed
US-20190167552-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR L'OREAL (FR) 2019-06-06 US claimed
US-20190117551-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER L'OREAL (FR) 2019-04-25 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0168277-B2 POLY(ORTHOESTER)POLYMERS CONTAINING PENDANT ACID FUNCTIONALITIES AND LABILE BACKBONE BONDS Merck & Co., Inc. (US) 1992-12-30 EP claimed
EP-0168277-B1 Poly(orthoester)polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO. INC. (US) 1990-08-01 EP claimed
US-4765973-A Polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO., INC. (US) 1988-08-23 US claimed
US-4639366-A Polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO., INC. (US) 1987-01-27 US claimed
EP-0168277-A1 Poly(orthoester)polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO. INC. (US) 1986-01-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B HPGD 1754/4885GABRP 4277/4885GABRD 4588/4885
US-20190167552-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR KRT18, OAT, CKMT1A; CKMT1B HPGD 2893/4885GABRP 3694/4885GABRD 4022/4885
US-11298305-B2 Compositions and methods for improving the appearance of the hair KRT18, OAT, CKMT1A; CKMT1B HPGD 2893/4885GABRP 3694/4885GABRD 4022/4885
US-20190117551-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER KRT18, CUTA, MARK1 HPGD 1037/4885GABRP 2483/4885GABRD 2882/4885
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone KRT18, CUTA, PUF60 HPGD 2565/4885GABRP 3774/4885GABRD 4382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.