SCHEMBL28062887

SCHEMBL28062887

O=CNc1cnc(O)nc1O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7944560 0.81 ADORA1 (0.33) KDM5A
SCHEMBL12106737 0.72
SCHEMBL14940691 0.72 TRIM24 (0.33)
SCHEMBL30009941 0.72 TRIM24 (0.33)
SCHEMBL30019416 0.72 KDM5A (0.33) KDM5A
SCHEMBL29011264 0.70 ALDH1A1 (0.41)
SCHEMBL19250211 0.66 PABPC1 (0.42) KDM5A
SCHEMBL23330860 0.65 KDM4E (0.41)
SCHEMBL6661385 0.65 DHFR (0.33)
SCHEMBL15435554 0.64 TSHR (0.42) KDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105646372-A Preparation method of 2-amino-4,6-dichloro-5-formamine pyrimidine 北京英力精化技术发展有限公司 2016-06-08 CN disclosed