Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719470 | 0.73 | MEN1 (0.40) | SIGMAR1AVPR1A | |
| SCHEMBL9420013 | 0.70 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL28600721 | 0.70 | SIGMAR1 (0.40) | SIGMAR1AVPR1A | |
| SCHEMBL30869312 | 0.70 | HTR2A (0.41) | SIGMAR1 | |
| SCHEMBL9615977 | 0.70 | SIGMAR1 (0.54) | SIGMAR1AVPR1A | |
| SCHEMBL25129913 | 0.70 | SIGMAR1 (0.40) | SIGMAR1AVPR1A | |
| SCHEMBL2619379 | 0.70 | HTR2A (0.41) | SIGMAR1 | |
| SCHEMBL28824800 | 0.70 | SIGMAR1 (0.36) | SIGMAR1AVPR1A | |
| SCHEMBL5685203 | 0.70 | OPRD1 (0.37) | SIGMAR1 | |
| SCHEMBL26077197 | 0.70 | SIGMAR1 (0.40) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354655-B | Bis-benzo [5,6] spiroketal compound and preparation method thereof | 威胜生物医药(苏州)股份有限公司 | 2022-12-13 | — | — | CN | disclosed |