Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 11/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 5/20 | 0.42 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202362 | 1.00 | GRIN1 (0.51) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL30012695 | 0.80 | GRIN1 (0.46) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL30110633 | 0.80 | GRIN1 (0.48) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL23393003 | 0.80 | GRIN1 (0.48) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL23202404 | 0.76 | ADORA2B (0.48) | GRIN1GRIN2BPDE4APDE4BPDE4C | |
| SCHEMBL30011489 | 0.76 | ADORA2B (0.48) | GRIN1GRIN2BPDE4APDE4BPDE4C | |
| SCHEMBL721924 | 0.75 | GRIN1 (0.64) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL23202297 | 0.73 | MEN1 (0.46) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL30013359 | 0.73 | MEN1 (0.46) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL481412 | 0.70 | MTOR (0.72) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533607-B | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-115427063-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |