Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202404 | 1.00 | ADORA2B (0.48) | ADORA2BADORA3CYP1A2TLR7GRIN1 | |
| SCHEMBL30012916 | 0.79 | ADORA3 (0.50) | ADORA2BADORA3GRIN1GRIN2B | |
| SCHEMBL30012911 | 0.79 | ADORA3 (0.50) | ADORA2BADORA3GRIN1GRIN2B | |
| SCHEMBL30110524 | 0.79 | ADORA3 (0.42) | ADORA2BADORA3CYP1A2GRIN1GRIN2B | |
| SCHEMBL23202127 | 0.79 | ADORA3 (0.42) | ADORA2BADORA3CYP1A2GRIN1GRIN2B | |
| SCHEMBL31392649 | 0.79 | ADORA3 (0.42) | ADORA2BADORA3GRIN1GRIN2B | |
| SCHEMBL23202362 | 0.76 | GRIN1 (0.51) | GRIN1GRIN2BPDE4APDE4BPDE4C | |
| SCHEMBL30011997 | 0.76 | GRIN1 (0.51) | GRIN1GRIN2BPDE4APDE4BPDE4C | |
| SCHEMBL23202181 | 0.68 | ADORA3 (0.43) | ADORA2BADORA3GLA | |
| SCHEMBL31392722 | 0.66 | ADORA2B (0.51) | ADORA2BADORA3GLABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533607-B | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3801538-B1 | TLR7 AGONISTS | PRIMMUNE THERAPEUTICS INC (US) | 2024-10-02 | — | — | EP | disclosed |
| CN-115427063-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |