SCHEMBL30012192

SCHEMBL30012192

CCOc1cc2ncc(C(N)=O)cc2cc1N1CCN(C)CC1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 8/20 0.54
KCNH2 Q12809 5/20 0.54
SCN5A Q14524 3/20 0.54
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HPGDS O60760 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MTOR P42345 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707366 0.80 HPGDS (0.54) KDM4EALDH1A1HSD17B10HPGDSMEN1
SCHEMBL6972474 0.77 HSD17B10 (0.59) CSF1RKCNH2SCN5AKDM4EALDH1A1
SCHEMBL6061808 0.76 HPGDS (0.49) CSF1RHPGDSMEN1KMT2ATSHR
SCHEMBL30011619 0.74 CHEK1 (0.53) CSF1RKDM4EALDH1A1HSD17B10HPGDS
SCHEMBL4223684 0.74 HRH4 (0.47) CSF1RKCNH2SCN5ASMN1; SMN2
SCHEMBL2907540 0.71 CSF1R (0.88) CSF1RKCNH2SCN5A
SCHEMBL1276777 0.71 CSF1R (1.00) CSF1RKCNH2SCN5A
SCHEMBL29411758 0.71 CSF1R (1.00) CSF1RKCNH2SCN5A
SCHEMBL2914405 0.70 CSF1R (0.70) CSF1RKCNH2SCN5AMEN1KMT2A
SCHEMBL2914050 0.70 CSF1R (0.78) CSF1RKCNH2SCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4073025-A1 METAL SALTS AND USES THEREOF Inspirna, Inc. (US) 2022-10-19 EP disclosed