Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.68 |
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | CASP3 | P42574 | 2/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20704747 | 0.79 | ALOX15 (0.60) | SMN1; SMN2MAPTTP53KMT2AMEN1 | |
| SCHEMBL20711026 | 0.76 | MEN1 (0.60) | SMN1; SMN2MAPTTP53KMT2AMEN1 | |
| SCHEMBL3456751 | 0.76 | SMN1; SMN2 (0.75) | SMN1; SMN2MAPTNPC1RAB9ACASP3 | |
| SCHEMBL20704783 | 0.75 | MEN1 (0.77) | MAPTRAB9ATP53KMT2AMEN1 | |
| SCHEMBL4141051 | 0.73 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPTNPC1RAB9ACASP3 | |
| SCHEMBL18430420 | 0.73 | HPGD (0.62) | SMN1; SMN2MAPTNPC1RAB9ACASP3 | |
| SCHEMBL29601906 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTNPC1RAB9ACASP3 | |
| SCHEMBL18430419 | 0.72 | HPGD (0.61) | SMN1; SMN2MAPTNPC1RAB9ACASP3 | |
| SCHEMBL20704820 | 0.72 | MEN1 (0.54) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL20704762 | 0.72 | MEN1 (0.68) | SMN1; SMN2MAPTNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11505528-B2 | Inhibitors of microbially induced amyloid | AXIAL THERAPEUTICS, INC. (US) | 2022-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11505528-B2 | Inhibitors of microbially induced amyloid | SNCA, PARK7, PRNP | SMN1; SMN2 1330/4885MAPT 7/4885NPC1 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.