Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 16/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 16/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31142194 | 0.88 | GRIN1 (0.40) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL30012811 | 0.85 | GRIN1 (0.40) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL31142195 | 0.83 | GRIN1 (0.39) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL31142199 | 0.80 | GRIN1 (0.39) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL30110608 | 0.77 | ADORA2A (0.49) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL23202176 | 0.76 | LMNA (0.37) | GRIN1GRIN2BMETAP2 | |
| SCHEMBL31142188 | 0.76 | GRIN1 (0.52) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL30012916 | 0.76 | ADORA3 (0.50) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL30012911 | 0.76 | ADORA3 (0.50) | GRIN1GRIN2BITGB1ITGAV | |
| SCHEMBL31142184 | 0.74 | GRIN1 (0.58) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |