Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577365 | 1.00 | HRH4 (0.43) | HRH4HRH3AMY1AHSD17B10LCK | |
| SCHEMBL30979120 | 0.84 | HRH4 (0.46) | HRH4HRH3MAPTFGFR1CDC7 | |
| SCHEMBL30979012 | 0.81 | HRH4 (0.43) | HRH4HRH3HSD17B10LCKMAPT | |
| SCHEMBL23577370 | 0.78 | HRH4 (0.43) | HRH4HRH3MAPTKMT2AKDM4E | |
| SCHEMBL29909232 | 0.78 | HRH4 (0.43) | HRH4HRH3MAPTKMT2AKDM4E | |
| SCHEMBL29909609 | 0.76 | KDM4E (0.37) | HRH4MAPTKDM4EALDH1A1HTT | |
| SCHEMBL23576802 | 0.76 | KDM4E (0.37) | HRH4MAPTKDM4EALDH1A1HTT | |
| SCHEMBL23577151 | 0.75 | ABCG2 (0.47) | HRH4HRH3MAPTFGFR1KMT2A | |
| SCHEMBL30014094 | 0.75 | ABCG2 (0.47) | HRH4HRH3MAPTFGFR1KMT2A | |
| SCHEMBL23576679 | 0.75 | PARP1 (0.46) | HRH4HRH3FGFR1L3MBTL1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |