Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013724 | 0.81 | HRH4 (0.43) | HRH4HRH3L3MBTL1MAPTKDM4E | |
| SCHEMBL30979120 | 0.81 | HRH4 (0.46) | HRH4HRH3MAPTALDH1A1FGFR1 | |
| SCHEMBL23577365 | 0.81 | HRH4 (0.43) | HRH4HRH3L3MBTL1MAPTKDM4E | |
| SCHEMBL30979084 | 0.78 | TOP2A (0.43) | MAPTKDM4ETOP2AALDH1A1 | |
| SCHEMBL23601428 | 0.78 | MAT2A (0.48) | HRH4MAPT | |
| SCHEMBL30978994 | 0.78 | TOP2A (0.40) | HRH4MAPTKDM4ETOP2AALDH1A1 | |
| SCHEMBL30979023 | 0.77 | MAPT (0.44) | HRH4HRH3L3MBTL1MAPTKDM4E | |
| SCHEMBL23577151 | 0.75 | ABCG2 (0.47) | HRH4HRH3L3MBTL1MAPTALDH1A1 | |
| SCHEMBL30014094 | 0.75 | ABCG2 (0.47) | HRH4HRH3L3MBTL1MAPTALDH1A1 | |
| SCHEMBL30979101 | 0.74 | TOP2A (0.37) | HRH4MAPTKDM4ETOP2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |