Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10185312 | 0.84 | SLC27A1 (0.47) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL3548512 | 0.83 | SLC27A1 (0.46) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| Hydrochloric Acid SCHEMBL21816391 | 0.83 | SLC27A1 (0.49) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL31032248 | 0.83 | LMNA (0.49) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL11187627 | 0.80 | LMNA (0.40) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL24927797 | 0.79 | SLC27A1 (0.44) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL29568081 | 0.79 | MAPK1 (0.43) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL20223639 | 0.79 | SLC27A1 (0.44) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL10185310 | 0.79 | AR (0.42) | SLC27A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL11195223 | 0.78 | MAPK1 (0.46) | SMN1; SMN2LMNAHPGDHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672952-B1 | BENZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | claimed |