Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304060 | 1.00 | AKR1B1 (0.61) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL30359 | 0.88 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL29410826 | 0.88 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Hydrogen Sulfide SCHEMBL27426416 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Hydrochloric Acid SCHEMBL9621764 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Hydrochloric Acid SCHEMBL6767821 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL28842838 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Iodide SCHEMBL31305035 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Methyl Alcohol SCHEMBL28299530 | 0.83 | AKR1B1 (0.70) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL7255216 | 0.82 | ALDH1A1 (0.41) | AKR1B1TDP1CXCL8PTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146308-A | Cyclic peptides for treating gastric cancer and pharmaceutical composition thereof | 中国科学院分子细胞科学卓越创新中心 | 2024-06-07 | — | — | CN | disclosed |
| EP-4291177-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY | Recovery Therapeutics, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-117157069-A | Compounds, compositions and methods for modulating FGF activity | 康复治疗公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2022174083-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY | RECOVERY THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |