Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015117 | 1.00 | AKR1B1 (0.61) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL30359 | 0.88 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL29410826 | 0.88 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Hydrogen Sulfide SCHEMBL27426416 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Hydrochloric Acid SCHEMBL9621764 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Hydrochloric Acid SCHEMBL6767821 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL28842838 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Iodide SCHEMBL31305035 | 0.85 | AKR1B1 (0.73) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| Methyl Alcohol SCHEMBL28299530 | 0.83 | AKR1B1 (0.70) | AKR1B1TDP1CXCL8PTGS1AKR1B10 | |
| SCHEMBL7255216 | 0.82 | ALDH1A1 (0.41) | AKR1B1TDP1CXCL8PTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606206-A | Preparation process of picoxystrobin intermediate methyl o-chloromethyl phenylacetate | 河北诚信集团有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-109456295-B | Micro-channel method synthesis process of 3-isochromanone | 苏州华道生物药业股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-112125876-A | Synthetic method of 3-isochromone | 宁夏思科达生物科技有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-1639113-B | Method for producing 2-chloromethylphenyl acetic acid derivatives | BASF AG | 2011-06-01 | — | — | CN | claimed |
| EP-1072580-B1 | PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID | IHARA CHEMICAL IND CO (JP) | 2010-12-01 | — | — | EP | claimed |
| US-20090177005-A1 | Method For Producing 2-(chloromethyl)penylacetic acid derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | US | claimed |
| US-7491834-B2 | Chemical process | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-17 | — | — | US | claimed |
| US-7488840-B2 | Method for producing 2-chloromethylphenyl acetic acid derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-10 | — | — | US | claimed |
| US-20060163159-A1 | Chemical process | SYNGENTA CROP PROTECTION, INC. | 2006-07-27 | — | — | US | claimed |
| EP-1480945-B1 | METHOD FOR PRODUCING 2-CHLOROMETHYLPHENYL ACETIC ACID DERIVATIVES | BASF AG (DE) | 2005-09-14 | — | — | EP | claimed |
| EP-0906265-B1 | CHEMICAL PROCESS | SYNGENTA LTD (GB) | 2001-08-29 | — | — | EP | claimed |
| EP-0906304-B1 | Process for preparing 3-isochromanone | SYNGENTA LTD (GB) | 2001-07-18 | — | — | EP | claimed |
| US-6215006-B1 | HYDROGEN CHLORIDE REMOVAL; ESTERIFICATION; DECHLORINATION; DEHYDROHALOGENATION | CLARIANT GMBH (DE) | 2001-04-10 | — | — | US | claimed |
| EP-1072580-A1 | PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID | Ihara Nikkei Chemical Industry Co., Ltd. (JP) | 2001-01-31 | — | — | EP | claimed |
| EP-1054009-A2 | Process for preparation of 3-isochromanones by cyclisation of o-chloromethylphenylacetic acids | Clariant GmbH (DE) | 2000-11-22 | — | — | EP | claimed |
| US-6008381-A | REACTING ORTHO-TOLYLACETIC ACID WITH SULFURYL CHLORIDE IN PRESENCE OF FREE RADICAL INITIATOR AND TREATING THE FORMED 2-CHLOROMETHYLPHENYLACETIC ACID WITH A BASE | ZENECA LIMITED (GB) | 1999-12-28 | — | — | US | claimed |
| EP-0906304-A1 | PROCESS FOR PREPARING 3-ISOCHROMANONE | ZENECA LIMITED (GB) | 1999-04-07 | — | — | EP | claimed |
| EP-0906265-A1 | CHEMICAL PROCESS | ZENECA LIMITED (GB) | 1999-04-07 | — | — | EP | claimed |
| WO-1997048692-A1 | PROCESS FOR PREPARING 3-ISOCHROMANONE | ZENECA LIMITED (GB) | 1997-12-24 | — | — | WO | claimed |
| WO-1997048671-A1 | CHEMICAL PROCESS | ZENECA LIMITED (GB) | 1997-12-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060163159-A1 | Chemical process | HAO2, OGDH, TST | AKR1B1 2477/4885TDP1 4044/4885CXCL8 4340/4885 |
| US-20090177005-A1 | Method For Producing 2-(chloromethyl)penylacetic acid derivatives | C5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PCCA | AKR1B1 2080/4885TDP1 4337/4885CXCL8 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.