Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26195525 | 1.00 | SLC7A5 (0.47) | SLC7A5PTPN1HDAC1HDAC2MDM4 | |
| SCHEMBL25354903 | 0.92 | SLC7A5 (0.52) | SLC7A5PTPN1MDM4TP53 | |
| SCHEMBL22636165 | 0.92 | SLC7A5 (0.52) | SLC7A5PTPN1MDM4TP53 | |
| SCHEMBL22636167 | 0.92 | SLC7A5 (0.52) | SLC7A5PTPN1MDM4TP53 | |
| SCHEMBL30229462 | 0.92 | SLC7A5 (0.52) | SLC7A5PTPN1MDM4TP53 | |
| SCHEMBL31210312 | 0.92 | SLC7A5 (0.52) | SLC7A5PTPN1MDM4TP53 | |
| SCHEMBL29634845 | 0.92 | SLC7A5 (0.52) | SLC7A5PTPN1MDM4TP53 | |
| SCHEMBL30229655 | 0.92 | SLC7A5 (0.47) | SLC7A5PTPN1MDM4TP53 | |
| SCHEMBL29017551 | 0.88 | IDO1 (0.48) | PTPN1HDAC1HDAC2MDM4TP53 | |
| SCHEMBL22636072 | 0.88 | SLC7A5 (0.57) | SLC7A5CTSLCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360179-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-10-31 | — | — | US | disclosed |
| EP-4355350-A1 | STAPLED PEPTIDES AND METHODS THEREOF | Fog Pharmaceuticals, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
| US-20230271917-A1 | AMINO ACIDS | PARABILIS MEDICINES, INC. | 2023-08-31 | — | — | US | disclosed |
| WO-2022261257-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | SLC7A5 4340/4885PTPN1 2414/4885HDAC1 3641/4885 |
| US-20240360179-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | SLC7A5 4492/4885PTPN1 2717/4885HDAC1 3347/4885 |
| US-20230271917-A1 | AMINO ACIDS | NPPA, QPCTL, PTMS | SLC7A5 678/4885PTPN1 3306/4885HDAC1 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.